Cosmetic preparations for revitalizing the skin

ABSTRACT

Cosmetic preparations revitalizing the skin which use products for external usage on the human body and a product for internal usage on the human body. The products for external usage are comprised by two creams and one solution, which stimulate the epidermal cells and the fibroblasts of the derma, while protecting the epidermis, and the product for internal usage is comprised by small gelatin capsule which carry to the fibroblasts of the derma amino acids and aligo-elements.

FIELD OF THE INVENTION

The present invention relates to the field of cosmetics.

The present invention concerns different cosmetic preparations whichrevitalize the skin, each preparation being enriched in vitamins.

The different preparations are usable externally, by simple spreading onthe skin, and by the oral route.

These two application routes act synergetically.

BACKGROUND OF THE INVENTION

Numerous documents relate to epidermal and dermal problems.

Thus, the document FR-A-2.585.568 relates to new cosmetic compositions,comprising a lipid derivative of corneous cells which can improve theability of the corneous layer to retain moisture. They are useful in thetreatment of dry skin. When the lipid is used in combination withtensio-active agents, the above effect is improved. The cosmeticcompositions can be present in any type of preparation, such as creams,milks, beauty masks, lip rouge, foundation base, capillary tonics andthe like.

This document discloses different types of preparations which can permitthe treatment of dry skin.

The document FR-A-2.631.824 relates to cosmetic compositions whichinclude in combination a component formed of a mixture of essentialaromatic oils extracted from plants selected from: Lavender, Geranium,Rosemary, Eucalyptus, Sage, Thyme, Juniper, Basil, myroxylon, Lahafiland a composition including vitamins A and E, of ginseng andgammalinoleic acid.

This document discloses the use of vitamins A and E and the use of plantextracts.

All of these documents treat the problem of revitalization of the skinonly by simple external application, promoting the retention of water bythe cells.

SUMMARY OF THE INVENTION

The present invention has for its object cosmetic preparationsrevitalizing the skin, of the type using products used externally on thehuman body and a product used internally of said human body,characterized by the fact that the products for external use arecomprised by two creams and one solution, which stimulate the epidermalcells and the fibroblasts of the derma and which protect the epidermisand in which the product for internal use is formed of small gelatincapsules which carry to the epidermal cells and to the fibroblasts,among others, amino acids and oligo-elements.

The invention also has for its object cosmetic preparationscharacterized by the fact that the total mass of the product forinternal use comprises 33.4 to 34.4 parts per 100, hereinafterrepresented by the percentage symbol %, of amino acids, 23.7 to 24.7% oflecithin, 22.1 to 23.1% of lyophilized royal jelly, 4.8 to 5.4% vitaminC, substantially 0.1% of vitamin B6, substantially 0.02% of vitamin B12,and substantially 0.02% of oligo-elements.

The invention also has for its object cosmetic preparationscharacterized by the fact that the amino acids are in equivalentproportions of lysine, serine, histidine, threonine, valine and/orleucine.

Another object of the present invention is to provide cosmeticpreparations characterized by the fact that the oligo-elements are inthe form of selenium, zinc, magnesium, iron, manganese, copper,potassium, cobalt, phosphorous, silicon, chromium and/or vanadium.

Another object of the present invention is to provide cosmeticpreparations characterized by the fact that the mass of each cream forexternal use comprises substantially 1% of essential oil of camomileromaine, substantially 1.5% of royal jelly, substantially 2% of wheatgerm oil, substantially 0.25% of vitamin A, substantially 0.25% ofvitamin E, substantially 0.25% of vitamin F, substantially 0.5% ofbiostimulants, and substantially 0.5% of allantoin.

Another object of the invention is to provide cosmetic preparationscharacterized by the fact that one of the two creams for external usecomprises a hydrating factor of vegetable origin which is substantially2.5% of the mass of said cream for external usage.

Another object of the present invention is to provide cosmeticpreparations characterized by the fact that the creams for external useuse as an excipient an emulsion of the oil-in-water type.

Another object of the invention is to provide cosmetic preparationscharacterized by the fact that the creams for external use have a pHsubstantially equal to 6.8.

Another object of the invention is to provide cosmetic preparationscharacterized by the fact that the mass of the solution for external usecomprises 9.5 to 10.5% of extracts of Aloe Vera enriched inbiostimulants, substantially 0.25% of vitamin A, substantially 0.25% ofvitamin E, and substantially 0.25% of vitamin F.

An object of the invention is to provide cosmetic preparationscharacterized by the fact that the solution for external use uses as anexcipient vegetable extracts enriched in natural hydrating factor.

Finally, the present invention has for its object the use of cosmeticpreparations characterized by the fact that the application of thesolution for external use precedes the application of the cream forexternal use which comprises the hydrating factor of vegetable origin.

DETAILED DESCRIPTION OF THE INVENTION

The description which follows is only by way of example and is notlimiting, of the cosmetic preparations of the invention.

The present invention has the advantage of treating the skin as it is,which is to say a complex organ of our organism.

Thus, it is necessary to impart to it a stimulation from the exteriorbut above all to supply it from the interior with the combination ofsubstances necessary for the biosynthesis of elastin and collagen, whichwill permit the skin to respond favorably to the external stimulation.

The external stimulation is by external factors such as biostimulantswhich have a role of general stimulation for all the epidermal cells aswell as the fibroblasts of the derma which synthesize the elastic matrixformed of collagen and elastin.

This biosynthesis of the fibroblasts depends on the content of thespecific amino acids which are lacking in the organism.

These substances, as well as the vitamins and oligo-elementsindispensable to this synthesis, can be supplied by the blood, fromwhich arises the need to use an internal factor in the form of adietetic product specific to the skin.

From this fact, the cosmetic preparations regenerating the skin are ofthe type using products for external use on the human body but also aproduct for internal use in said human body.

The products for external use stimulate all of the epidermal cells aswell as the fibroblasts located in the derma and, moreover, permit therevitalization and hydration of the epidermis.

The product for internal use, for its part, carries several elementssuch as the amino acids and the oligo-elements.

Nevertheless, it is well to specify that a mixture comprising a randommixture of vitamins, oligo-elements and amino acids is not necessarilythe most effective.

The product for internal use is comprised by amino acids, lecithin,lyophilized royal jelly, vitamins and oligo-elements.

The products for external use are comprised by two creams and onesolution.

The creams for external use are comprised of essential oils, camomileromaine, lyophilized royal jelly and wheat germ oil, vitamins,biostimulants and allantoin, while the solution for external use iscomprised by vitamins, extracts of Aloe Vera, and biostimulants.

The solution for external use uses as an excipient vegetable extractsenriched in natural hydrating factor such as tea extracts.

As to the product for internal use, the mass of this latter comprises33.9% of amino acids.

These amino acids are, in equivalent proportion to each other, lysine,serine, histidine, threonine, valine and/or leucine.

The mass of the product for internal use comprises also 24.2% oflecithin, 22.6% of lyophilized royal jelly, 19.7% of vitamins of whichthe vitamins C, B6 and B12 that are present in the respective followingproportions: 5.1%, 0.1% and 0.02%.

The oligo-elements are numerous and essential in the biosynthesis ofelastin and collagen.

They comprise selenium, zinc, magnesium, iron, manganese, copper,potassium, cobalt, germanium, phosphorus, silicon, chromium and/orvanadium.

The oligo-elements are in substantially equivalent proportion to eachother and comprise 0.02% of the mass of the product for internal use.

The two creams for external usage have a composition that is identicalapart from one element.

Thus, the mass of each cream for external use comprises 1% essential oilof camomile romaine, 1.5% of royal jelly, 2% of wheat germ oil, 0.75% ofvitamins distributed in equal proportion between vitamins A, E and F,0.5% of biostimulants and 0.5% of allantoin.

One of the two creams, for day-time use, comprises moreover a hydratingfactor of vegetable origin which is present in a proportion of 2.5% inthe mass of the cream for external use that contains it.

The other cream is for night-time use.

The creams for external use, whether day time or night time, use asexcipient an emulsion of the oil-in-water type which permits havingcreams for external use which have the property of having a high pHequal to 6.8.

The last product of these cosmetic preparations is the solution forexternal usage.

The mass of this latter comprises 10% of Aloe Vera extracts, 0.5%biostimulants, but also 0.75% of vitamins distributed in the followingfashion: 0.25% of vitamins A, 0.25% of vitamin E and 0.25% of vitamin F.

This solution for external use has for its excipient vegetable extractsenriched in natural hydrating factor, such as tea extracts.

Numerous studies and tests under dermatological hospital conditions havepermitted establishing the safety of the cosmetic preparations of thepresent invention and demonstrating the revitalizing regenerating actionof these latter.

The object of these studies has been to ascertain the properties ofcomplete treatment utilizing the two creams, one for day, the other fornight, and the solution, as well as the product for internal usage, thislatter being present in the form of small gelatin capsules.

A study of the results has been possible because the two creams havebeen applied over all the face while the solution has been applied onlyon the right-hand half of the face.

This has been performed on six volunteer adult subjects for a total of40 days.

The results which are given below represent the measures taken from thefirst through the fortieth day.

The administration of the small gelatin capsules was daily, three timesper day which is to say morning, noon and night.

The application of the day regenerating cream was daily, at 8:00 o'clockin the morning.

The use of the regenerating and firming night cream was daily, at about10:00 p.m.

The use of the solution was daily, about 8:00 a.m.

The use of the solution always precedes the application of theregenerating and hydrating day cream.

Prints on the skin were produced with the help of a synthetic polymerespecially used for this purpose.

The reading of the prints permitted identifying two zones: the flatportions and the wrinkles on the forehead.

The results are expressed in percentages corresponding to the surface ofthe skin forming the flat regions and the wrinkles relative to 100% ofthe skin surface studied as a reference.

                  TABLE I                                                         ______________________________________                                        STUDIES OF FLAT SURFACES                                                                 Right Side (%)                                                                          Left Side (%)                                            ______________________________________                                        DAY 1        65.05       65.98                                                DAY 40       67.81       66.47                                                ______________________________________                                    

There will be noted from this table, the tendency to enlarge the flatareas.

However, between the right side and the left side an importantdifference appears.

Between day 1 designated DAY 1 and day 40 designated DAY 40, there willbe noted on the right side an increase of 2.76% of the surface of theflat areas, while on the left side the increase is only 0.49%.

It therefore appears clearly that the right side half face to which wasapplied the solution, has developed more favorably than the left sidehalf face.

                  TABLE II                                                        ______________________________________                                        STUDY OF WRINKLES                                                                        Right Side (%)                                                                          Left Side (%)                                            ______________________________________                                        DAY 1        31.54       30.31                                                DAY 40       28.58       30.07                                                ______________________________________                                    

Here again, the effects on the depths of the wrinkles are not the samebetween the right side and the left side.

The differences which exist between the two sides are even moreimportant.

It will be noted that respectively the right side has a decrease of2.96% of the surplus area of the wrinkles, while on the left side thisdecrease is only 0.24%.

Here again, the presence of the solution containing biostimulantspermits acting directly on the epidermal cells.

                  TABLE III                                                       ______________________________________                                        STUDY OF THE THICKNESS OF THE EPIDERMIS                                                   DAY 1    DAY 40                                                               (micrometers)                                                                          (micrometers)                                            ______________________________________                                        1st subject   56.88      67.18                                                2nd subject   60.94      76.29                                                3rd subject   60.63      61.15                                                4th subject   56.20      62.41                                                5th subject   64.99      68.78                                                6th subject   61.98      70.68                                                ______________________________________                                    

From this last table will be better understood the variations of theright-half side of the face of the subjects.

Thus, between the first and fortieth day of treatment, the six subjects,whose thickness of epidermis are indicated in the above table, show asubstantial thickening of said epidermis.

This method consists therefore in treating the skin from the exteriorand the interior at the same time with complementary active substanceswhich act at the tissue level of the skin, while taking part together inthe processes of revitalization of said skin with proven effects on thethickening of the skin, on its hydration, on the enlargement of the flatsurfaces and on the diminution of the wrinkles.

The effects on the derma are the increase of the elastin and collagenfibers which add themselves to the pre-existing fibers, which redoundsto the advantage of the skin.

I claim:
 1. Cosmetic preparation for regenerating the skin, comprising:products for external usage on the human body and a product for internalusage on said human body, said products for external usage comprising a)two creams comprised of essential oils, wheat germ oil, vitamins,biostimulants and allantoin, and b) one solution comprised of Aloe Veraextracts, biostimulants and vitamins, said two creams and one solutionworking together to stimulate the epidermal cells and the fibroblasts ofthe derma, and to protect the epidermis, andsaid product for internalusage comprised of amino acids, lecithin, lyophilized royal jelly,vitamins and oligo-elements.
 2. Preparation according to claim 1,wherein the total mass of the product for internal usage comprises:from33.4 to 34.4% of amino acids, from 23.7 to 24.7% of lecithin, from 22.1to 23.1% of lyophilized royal jelly, from 4.8 to 5.4% of vitamin C,substantially 0.1% of vitamin B6, substantially 0.02% of vitamin B12,and substantially 0.02% of oligo-elements.
 3. Preparation according toclaim 1, wherein the amino acids are selected from the group consistingof lysine, serine, histidine, threonine, valine and leucine, said aminoacids being present in equivalent proportions.
 4. Preparation accordingto claim 1, wherein the oligo-elements are selected from the groupconsisting of selenium, zinc, magnesium, iron, manganese, copper,potassium, cobalt, germanium, phosphate, silicon, chrome and vanadium.5. Preparation according to claim 1, wherein the mass of each cream forexternal usage comprises:substantially 1% of essential oil of camomileromaine, substantially 1.5% of royal jelly, substantially 2% of wheatgerm oil, substantially 0.25% of vitamin A, substantially 0.25% ofvitamin E, substantially 0.25% of vitamin F, substantially 0.5% ofbiostimulants, and substantially 0.5% of allantoin.
 6. Preparationaccording to claim 1, wherein one of the two creams is for day-time useand additionally comprises a hydrating factor of vegetable originrepresenting substantially 2.5% of the mass of said cream for day-timeuse.
 7. Preparation according to claim 1, wherein the creams forexternal usage use as an excipient an emulsion of the oil-in-water type.8. Preparation according to claim 1, wherein the creams for externalusage have a pH of about 6.8.
 9. Preparation according to claim 1,wherein the mass of the solution for external usage comprises:from 9.5to 10.5% of extracts of Aloe Vera, substantially 0.5% of biostimulants,substantially 0.25% of vitamin A, substantially 0.25% of vitamin E, andsubstantially 0.25% of vitamin F.
 10. Preparation according to claim 1,wherein the solution for external usage utilizes as an excipientvegetable extracts enriched in natural hydrating factor.
 11. Preparationaccording to claim 1, wherein use of the solution for external usageprecedes the application of one of the creams for external usage. 12.Preparation according to claim 1, wherein the product for internal usageis in the form of gelatin capsules, which carry said amino acids andoligo-elements to the epidermal cells and to the fibroblasts.